News.

With a stunning talk on the experiments and results Joel made throughout his Master's, Joel successfully defended his thesis! Great job, Joel! We're super proud of you and are so happy to have shared so many lovely memories with you :)

Together with researchers from the National Institute of Health and the University of Geneva, our department of immunology was part of an international consortium that identified a new genetic disease caused by mutations in the GNAI2 gene. Read more about how it was discovered, the disease itself, and a potential novel treatment here:
English: https://www.unige.ch/medecine/en/public-outreach/media/A-new-rare-genetic-disease-identified
French: https://www.unige.ch/medecine/faculteetcite/media/decouverte-dune-nouvelle-maladie-genetique-rare

Link to Publication in Science: https://doi.org/10.1126/science.add8947

Today marks the day we've officially moved to the new building. Find us in the brand new Children's Hospital Research tower at August-Forel-Strasse 51.

Tommaso officially defended his PhD thesis titled "Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation”. Congratulations on your great success, Dr. Tommaso! :)

All good things must come to an end! The Kispi labs at August-Forel-Strasse 7 will soon move to our new homes in the new research tower of the Children's Hospital. So, we celebrated our wonderful time here with a final "Ustrinkete" and reminisced in the memories of the past few years. Cheers to all the lovely people of AFS!

His work on finding out how cytokine-induced cell exhaustion mitigates hyperinflammation is now available on bioRxiv. Read more about the direction Tommaso took from an early hypothesis to finding a novel therapeutic strategy for HLH here: https://doi.org/10.1101/2024.08.12.607544

Today, the entire immunology departement wend on a wonderful BBQ on a boat on lake Zurich. Cheers to an amazing department!

Nadine joins our lab as a Master student after joining our lab for the block course BME362 in 2023. Welcome Nadine!

We warmly welcome Julius, who will start his PhD in our lab! Due to his completed medical education, Julius will be a natural talent at bridging the gap between clinic and research. Glad you're with us Julius!

The subject of his thesis is "Multiplexed Imaging-based Profiling of Immunological Synapses as a Novel Tool for Characterization of Cytotoxicity Defects in Primary Immunodeficiencies". Congratulations Danil!

After his first experience in the lab as part of the BME362 block course in 2022, Joel joins the lab for his Master thesis! Joel will be working with Ola Sabet to investigate the role of ZNFX1 in the immune system. Welcome Joel!

From the far east at Zhejiang University, Junyi has found his way to our lab. He did his Master thesis on the role of ferroptosis in chronic diseases, and after some work as a research associate in oncology, Junyi now joins us to investigate the immune system. Welcome, Junyi!

We took some time off work. Not to relax - or, well, not ONLY to relax - but to think about where the lab is, and where we want it to go. The lovely location of Weggis with a seminar room right next to the lake let our minds bloom and wander. Off to the next year, and the next retreat soon!

We are excited to announce that Tiziana Lorenzini has joined our lab as a post-doc. Tiziana worked as a medical doctor in Italy, where she found a love for science! She then started her PhD in Roland Martin's lab where she worked on multiple sclerosis.

With Tiziana's background in both clinic and science, she will be integrating new clinical findings with scientific research. We're looking forward to having you with us - welcome Tiziana!

Steffi joined our lab in 2019 as a lab manager. Now,  she will move on to finish her studies and pursue her dreams outside of the lab. We were incredibly lucky to have such a talented, passionate, and organized lab manager. You were an amazing friend and colleague - and we will all miss you dearly!

The Pachlopnik Lab hosted this years meeting of the Arbeitsgruppe Pädiatrische Immunologie (API) in the beautiful monastery of Kartause Ittingen, Switzerland. We had a packed program with great talks and a memorial for Prof. Walter Hitzig. We thank all the speakers and participants for a wonderful meeting. See you all next year!

We're excited to welcome Ola Sabet as senior scientist to the Pachlopnik Lab! Ola has a profound background in imaging, as well as programming and statistical analysis. She has been working as a post-doc in the Pelkmans Lab where she developed a super-resolution microscopy technique, glancing into the depths of cells. She will follow her interests in our lab, too, and work on imaging the immune system. Welcome Ola!

We welcome the newest member to our lab, Severin Walser! Severin has recently completed his Master's in the Pelkmans Lab, where he tackled the dynamics of mRNA in hiPSCs. With a background in imaging, sequencing, and programming, he will assist our efforts in characterizing genetic and molecular origins of monogenic immune diseases. Welcome Severin!