Pachlopnik Lab.

Understanding
Primary Immunodeficiencies
UZHlogo.png
Kispi-logo---BV (1).jpg
Kinderspital_Forschungszentrum_DE_RGB.jp
LifeScience_graduate_logo.jpg

ABOUT.

Our lab focuses on inborn errors of the immune system and their consequences on health - often an increased susceptibility to infections or an immune dysregulation. Many severe forms of immune defects affect babies and children when coming into first contact with pathogens. Treatment of patients is very dependent on the type of immune defect. We focus on patients, in whom routine diagnosis does not find the cause of the disease or  disease cause is not well understood.

We have established a joint genomic and transcriptomic workflow, combined with thorough functional and phenotypical examinations of leukocytes and fibroblasts from patients with extreme immunological phenotypes. Analyses of these datasets in combination with functional validation in animal models enabled us to identify novel diseases to better characterize pathomechanisms of known inborn error of immunity and to apply targeted treatments.

 
 

OUR RESEARCH.

We are interested in studying disease mechanisms.

Our goal is to broaden the knowledge of human immunology and improve treatment for patients with immune diseases.

 

OUR TEAM.

Principal Investigator

  • Pubmed_edited
  • Google_Scholar_edited_edited
  • ResearchGate_edited
Jana Pachlopnik Schmid
Prof MD PhD

Senior Post-Doc

  • orcid-og-image_edited

Bioinformatician

  • Pubmed_edited
  • Google_Scholar_edited_edited
Lennart
Opitz
MSc

Lab Manager

PhD Student

Sonja
Brun

Study Nurse

Sonja
Brun
Esther
Gujer

MMed Student

Esther
Gujer
Michael
Killian

MMed Student

Michael
Killian
Samantha Milanesi
PhD

Post-Doc

Samantha Milanesi
 
PhD

PhD Student

Katri
Eskola

Study Nurse

Katri
Eskola
Lars
Malmström

PhD

Bioinformatitian

Lars
Malmström

PhD
Diana
Tintor

MSc

PhD Student

Diana
Tintor


MSc
Seraina
Prader
MD

Medical Doctor

Seraina
Prader

MD
 
 
 
 
 

LATEST PUBLICATIONS.

 

COLLABORATIONS.

FUNDS.

Ederer.jpg
Screenshot 2020-05-12 at 16.14.40.png
Novartis_logo.png
 
Screenshot 2020-05-11 at 16.45.57.png
 

HOW TO FIND US.

ADDRESS: AUGUST FOREL STRASSE 7, 8008 ZURICH, SWITZERLAND

TEL: +41 44 635 29 31  |  Immuno.Forschung@kispi.uzh.ch

  • Twitter