Pachlopnik Lab.

Understanding
Primary Immunodeficiencies
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ABOUT.

Our lab focuses on inborn errors of the immune system and their consequences on health - often an increased susceptibility to infections or an immune dysregulation. Many severe forms of immune defects affect babies and children when coming into first contact with pathogens. Treatment of patients is very dependent on the type of immune defect. We focus on patients, in whom routine diagnosis does not find the cause of the disease or  disease cause is not well understood.

Using whole exome sequencing we aim at finding the disease-causing mutation. As a next step, we characterize the consequences of the mutation with different methods, such as targeted mutations in cell lines, immunological assays, cytometry and multiplexed imaging. Our goal is to identify the molecular mechanisms that underlie these diseases, an essential  prerequisite for the identification of targeted treatment strategies.

 
 

OUR RESEARCH.

We are interested in studying disease mechanisms.

Our goal is to broaden the knowledge of human immunology and improve treatment for patients with immune diseases.

HLH
CYTOTOXICITY
AND
 CYTOKINES
TTC7
IMAGING
DISEASES
COVID-19
 

OUR TEAM.

Jana Pachlopnik Schmid
Prof MD PhD
Lennart
Opitz
MSc
Sina
Weiss
Sonja
Brun
Esther
Gujer
Michael
Killian
Raquel
Planas
 
PhD
Ursina
Nüesch
 
PhD
Katri
Eskola
Seraina
Prader
MD
 
 
 
 
 

LATEST PUBLICATIONS.

 

COLLABORATIONS.

FUNDS.

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ADDRESS: AUGUST FOREL STRASSE 7, 8008 ZURICH, SWITZERLAND

TEL: +41 44 635 29 31  |  Immuno.Forschung@kispi.uzh.ch

HOW TO FIND US.

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